ESR12: Nanotechnology-driven construction of bioanalytical devices for glycomics

Location: Institute of Chemistry, Slovakian Academy of Sciences (ICSAS), Bratislava, SK

Supervisor: Dr Ján Tkáč

The research will involve application of various types of nanomaterials to enhance sensitivity of detection using an optical and an electrochemical platform of detection. Such devices will be constructed using immobilised glycans, antibodies, commercially available lectins, artificial/recombinant lectins and various glycan binding modules developed within consortium. In the final steps lectins or newly developed glycan binding modules will be used for glycoprofiling of attached glycoproteins (i.e. a sandwich configuration antibodies/glycoproteins/lectins). Bioanalytical devices with immobilised glycans will be applied for specific detection of autoantibodies raised against aberrant glycans appearing during development and progression of various diseases.

Applicants should meet the following eligibility criteria:

  • Have a Diploma and/or a Master Degree in Biotechnology / Biochemistry / Analytical Chemistry or other related field relevant to the described research.
  • Have less than 4 years research experience at the signature of the contract (measured from the time the Master’s degree has been obtained).
  • Not have a PhD already.
  • Not have resided or carried out main activity in Slovakia for more than 12 months in the last 3 years immediately prior to the reference recruitment date.
  • Excellent knowledge of the English language (spoken and written / proficiency level)

The ESR will be contractually employed by the Institute of Chemistry, Slovak Academy of Sciences and will receive a Monthly Living Allowance plus a Mobility Allowance compliant with the applicable EC Marie Skłodowska-Curie Actions-ITN general conditions.

Application procedure:

Candidates should submit a CV, cover letter and the names and contact details of at least 3 references by e-mail to Jan.Tkac@savba.sk indicating reference ESR12 in the subject.

The deadline for application is 07/01/2019

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