SynBIOcarb Publications
Structure and Engineering of Tandem Repeat Lectins
Authors: Simona Notova, François Bonnardel, Frédérique Lisacek, Annabelle Varrot and Anne Imberty.
The Lectin LecA Sensitizes the Human Stretch-Activated Channel TREK-1 but Not Piezo1 and Binds Selectively to Cardiac Non-myocytes
Authors: Elisa Darkow, Eva Rog-Zielinska, Josef Madl, Annette Brandel, Lina Siukstaite, Ramin Omidvar, Peter Kohl, Ursula Ravens, Winfried Romer and Remi Peyronnet.
Polyvalent Transition-State Analogues of Sialyl Substrates Strongly Inhibit Bacterial Sialidases
Authors: Coralie Assailly, Clarisse Bridot, Amélie Saumonneau, Paul Lottin, Benoit Roubinet, Eva-Maria Krammer, Francesca François, Federica Vena, Ludovic Landemarre, Dimitri Alvarez Dorta, David Deniaud, Cyrille Grandjean, Charles Tellier, Sagrario Pascual, Véronique Montembault, Laurent Fontaine, Franck Daligault, Julie Bouckaert, Sébastien G. Gouin.
Electrochemical Impedance Spectroscopy on 2D Nanomaterial MXene Modified Interfaces: Application as a Characterization and Transducing Tool
Authors: Juvissan Aguedo, Lenka Lorencova, Marek Barath, Pavol Farkas and Jan Tkac.
Involvement of N‐glycans in Binding of Photorhabdus Luminescens Tc Toxin
Authors: Peter Njenga Ng’ang’a, Lina Siukstaite , Alexander Lang, Hans Bakker, Winfried Römer, Klaus Aktories and Gudula Schmidt.
Structural Diversities of Lectins Binding to the Glycosphingolipid Gb3
Authors: Lina Siukstaite , Anne Imberty and Winfried Römer.
Piggybacking on the Cholera Toxin: Identification of a Toxoid-binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons
Authors: Matthew Balmforth, Jessica Haigh, Christian Tiede, Darren Tomlinson, Jim Deuchars, Michael E. Webb, and W. Bruce Turnbull.
The Two Sweet Sides of Janus Lectin Drive Crosslinking of Liposomes to Cancer Cells and Material Uptake
Authors: Lina Siukstaite, Francesca Rosato, Anna Mitrovic, Peter Fritz Müller, Katharina Kraus, Simona Notova, Anne Imberty and Winfried Römer.
Identification of Whole-Serum Glycobiomarkers for Colorectal Carcinoma Using Reverse-Phase Lectin Microarray
Authors: Tomas Berto, Aniko Bertokova, Eduard Jane, Michal Hires, Juvissan Aguedo, Maria Potocarova, Ludovit Lukac, Alica Vikartovska, Peter Kasak, Lubor Borsig and Jan Tkac.
Homo- and Heterovalent Neoglycoproteins as Ligands for Bacterial Lectins
Authors: David Goyard, Benoît Roubinet, Federica Vena, Ludovic Landemarre and Olivier Renaudet.
A pore-forming β-trefoil lectin with specificity for the tumor-related glycosphingolipid Gb3
Authors: Simona Notova, François Bonnardel, Francesca Rosato, Lina Siukstaite, Jessica Schwaiger, Nicolai Bovin, Annabelle Varrot, Winfried Römer, Frédérique Lisacek, Anne Imberty.
Microbial Carbohydrate-binding Toxins – from Etiology to Biotechnological Application
Authors: Natalia Danielewicz, Francesca Rosato, Wenyue Dai, Winfried Römer, W. Bruce Turnbull and Juergen Mairhofer.
In-Depth Characterization of a Re-Engineered Cholera Toxin Manufacturing Process Using Growth-Decoupled Production in Escherichia coli
Authors: Natalia Danielewicz, Wenyue Dai, Francesca Rosato, Michael E. Webb, Gerald Striedner, Winfried Römer, W. Bruce Turnbull and Juergen Mairhofer.
Novel lectin-based Chimeric Antigen Receptors Target Gb3-positive Tumour Cells
Authors: Ana Valeria Meléndez, Rubí M.-H. Velasco Cárdenas, Simon Lagies, Juliane Strietz, Lina Siukstaite, Oliver S. Thomas, Jana Tomisch, Wilfried Weber, Bernd Kammerer, Winfried Römer and Susana Minguet.
The Choanoflagellate Pore-forming Lectin SaroL-1 Punches Holes in Cancer Cells by Targeting the Tumour-related Glycosphingolipid Gb3
Authors: Simona Notova, François Bonnardel , Francesca Rosato, Lina Siukstaite, Jessica Schwaiger, Jia Hui Lim, Nicolai Bovin, Annabelle Varrot, Yu Ogawa, Winfried Römer, Frédérique Lisacek and Anne Imberty.
Building an Artificial Plant Cell Wall on a Lipid Bilayer by Assembling Polysaccharides and Engineered Proteins
Authors: Simona Notova, Nathan Cannac, Luca Rabagliati, Maeva Touzard, Josselin Mante, Yotam Navon, Liliane Coche-Guérente, Olivier Lerouxel, Laurent Heux, and Anne Imberty.
MXene as a Novel Cartridge for N-glycan Enrichment
Authors: Juvissan Aguedo, Zuzana Pakanova, Lenka Lorencova, Marek Nemcovic, Peter Kasak, Marek Barath, Pavol Farkas, and Jan Tkac.
Extending Janus Lectins Architecture: Characterization and Application to Protocells
Authors: Simona Notova, Lina Siukstaite, Francesca Rosato, Federica Vena, Aymeric Audfray, Nicolai Bovin, Ludovic Landemarre, Winfried Römer and Anne Imberty.
Membrane Fusion Mediated by Non-covalent Binding of Re-engineered Cholera Toxin Assemblies to Glycolipids
Authors: Sarah Wehrum, Daniel Williamson, Lina Siukstaite, Thomas Branson, Taras Sycha, Josef Madla, Gemma Wildsmith, Wenyue Dai, James F. Ross, Maren Thomsen, Michael E. Webb, Winfried Römer and W. Bruce Turnbull.
Neutralizing the Impact of the Virulence Factor LecA from Pseudomonas Aeruginosa on Human Cells with New Glycomimetic Inhibitors
Authors: Eva Zahorska, Francesca Rosato, Kai Stober, Sakonwan Kuhaudomlarp, Joscha Meiers, Dirk Hauck, Dorina Reith, Emilie Gillon, Katharina Rox, Anne Imberty, Winfried Römer and Alexander Titz.
A Bispecific, Crosslinking Lectibody Activates Cytotoxic T Cells and Induces Cancer Cell Death
Authors: Francesca Rosato, Rajeev Pasupuleti, Jana Tomisch, Ana Valeria Meléndez, Dajana Kolanovic, Olga N. Makshakova, Birgit Wiltschi and Winfried Römer.
Stabilization of Membrane Topologies by Proteinaceous Remorin Scaffolds
Authors: Chao Su, Marta Rodriguez-Franco, Beatrice Lace, Nils Nebel, Casandra Hernandez-Reyes, Pengbo Liang, Eija Schulze, Evgeny V Mymrikov, Nikolas M Gross, Julian Knerr, Hong Wang, Lina Siukstaite, Jean Keller, Cyril Libourel, Alexandra AM Fischer, Katharina E Gabor, Eric Mark, Claudia Popp, Carola Hunte, Wilfried Weber, Petra Wendler, Thomas Stanislas, Pierre-Marc Delaux, Oliver Einsle, Robert Grosse, Winfried Römer and Thomas Ott.
Targeted Delivery of Oligonucleotides using Multivalent Protein–Carbohydrate Interactions
Authors: Vajinder Kumar and W. Bruce Turnbull.
Enzymatic Glyco-Modification of Synthetic Membrane System
Authors: Dylan Jabeguero, Lina Siukstaite, Chunyue Wang, Anna Mitrovic, Serge Pérez, Olga Makshakova, Ralf P. Richter, Winfried Römer and Christelle Breton.
Tuning Specificity and Topology of Lectins through Synthetic Biology
Authors: Simona Notova, Anne Imberty.
Clickable Shiga Toxin B Subunit for Drug Delivery in Cancer Therapy
Authors: Natalia Danielewicz, Francesca Rosato, Jana Tomisch, Jonas Gräber, Birgit Wiltschi, Gerald Striedner, Winfried Römer, and Juergen Mairhofer.
Other Synthetic Glycobiology Publications
Polymers of a Transition-state Sialyl Cation Strongly
Inhibit Bacterial Sialidases
Authors: Dimitri Alvarez-Dorta, Coralie Assailly, Clarisse Bridot, Amélie Saumonneau, Paul Lottin, Benoit Roubinet, Eva-Maria Krammer, Francesca François, Federica Vena, Ludovic Landemarre, et al.
Decoupling Protein Production from Cell Growth Enhances the Site-Specific Incorporation of Noncanonical Amino Acids in E. coli
Authors: Meritxell Galindo Casas, Patrick Stargardt, Juergen Mairhofer, and Birgit Wiltschi.
Bacteriophage Inspired Growth-Decoupled Recombinant Protein Production in Escherichia coli
Authors: Patrick Stargardt, Lukas Feuchtenhofer, Monika Cserjan-Puschmann, Gerald Striedner, and Juergen Mairhofer.
The Royal Society: Interface Focus – Synthetic Glycobiology
Authors: W Bruce Turnbull, Anne Imbert, Ola Blixt.